The lord of the 6th house in the 12th house of the horoscope

The ruler of the 6th house in the 12th house. Poor health, poor occupations, dishonest workers, losses because of employees or servants, an unhappy uncle, an absence of sexual satisfaction, diseases of the anus, problems with hearing in the left ear, poor sight in the left eye. (James Braha)

The lord of the 6th house in the 12th house. The classical texts mention, and experience confirms, the useless spending of one's money, nasty habits, an interest in the study of antiquity, sickliness, an interest in other people's spouses. (Tom Hopke)

The lord of the 6th house in the 12th house: he causes torment to other people, deals harshly with opponents, is hostile towards educated people, spends on vicious habits, is greedy for other people's property, relies on luck and is in no hurry to make an effort, possesses dubious moral qualities, lives long. (Shri G.S. Agarwal)

BPHS 26:72. In the case where the ruler of the 6th bhava is placed in the 12th bhava, money is <always> spent on vices, the native is unfriendly towards knowledgeable and learned people and treats animals cruelly <torments them>.

Comments: The placement of the ruler of the 6th bhava [house] in the 12th bhava will be very favourable for those born with the Mesha [Aries] Lagna, because with this Lagna Buddha [Mercury] gives ruinous results and, placed in the 12th bhava, it will be in its rashi [sign] of debilitation and therefore will be extremely weakened; thus its ruinous nature and its power to bring evil will be completely destroyed. Consequently, its malefic results will be completely neutralised. With all Lagnas the native will have a dubious character and he will always be inclined to go to other men's wives.

(“Brihat Parashara Hora Shastra”)